欢迎来到艾兰博曼,请 登录 | 立即注册
查看: 863|回复: 2

【资讯翻译】HPV vaccination may be effective in reducing abnormal Pap t...

[复制链接]

10

听众

10

收听

1954

积分

管理员

Rank: 9Rank: 9Rank: 9

积分
1954
发表于 2014-7-31 08:33:24 | 显示全部楼层 |阅读模式
HPV vaccination may be effective in reducing abnormal Pap test results even after sexual debut

Minority women who received the Human Papillomavirus Vaccination (HPV) even after becoming sexually active had lower rates of abnormal Pap test results than those who were never vaccinated. These findings appear in the journal Sexually Transmitted Diseases.

Researchers from Boston University School of Public Health and School of Medicine conducted a cross-sectional study of 235 women age 21 to 30 undergoing routine cervical cytology testing. HPV status and demographic and behavioral characteristics were self-reported and verified with electronic medical records.

"Although data clearly indicate better immune responses and vaccine efficacy against both genital warts and cervical dysplasia when vaccination occurs before age 14, this study suggests that HPV vaccination may be effective in reducing abnormal Pap test results even after sexual debut," explained co-author Rebecca Perkins, MD, MSc, assistant professor of Obstetrics and Gynecology at Boston University School of Medicine and a gynecologist at Boston Medical Center.

At the time of the study, 41 percent had received at least one HPV vaccination; 97 percent of women were vaccinated after sexual debut. Ten percent of women had an abnormal cervical cytology result. The prevalence of abnormal cytology was 65 percent lower in women who received at least one HPV vaccination as compared to unvaccinated women.

According to the researchers continued surveillance of HPV vaccination is necessary to identify clinical benefits, particularly given the low rate of vaccine uptake and completion and vaccination of many young women after sexual debut. "Studies should continue to compare vaccine effectiveness before and after sexual debut and by vaccine doses received and to explore the role of herd immunity," added Perkins.



信源地址:http://www.eatg.org/news/170628/ ... _after_sexual_debut

6

听众

0

收听

500

积分

版主

Rank: 7Rank: 7Rank: 7

积分
500
发表于 2014-7-31 15:02:19 | 显示全部楼层
认领~

6

听众

0

收听

500

积分

版主

Rank: 7Rank: 7Rank: 7

积分
500
发表于 2014-7-31 15:56:03 | 显示全部楼层
初次性生活后接种HPV疫苗或仍有效

在性活跃期接种人乳头瘤病毒(HPV)疫苗的少数女性所获得的巴氏涂片检查结果异常率低于未接种疫苗女性。该结果发表于《Sexually Transmitted Diseases(性传播疾病)》杂志。

来自于波士顿大学公共卫生学院和医学院的研究人员进行了一项横断面研究,受试者为235名接受常规宫颈细胞学检测的21-30岁女性。HPV状态、人口统计及行为特征根据受试者的自我报告记录并采用电子病历核实归档。

“此前数据清晰地表明14岁前接种疫苗在预防生殖器疣及宫颈非典型增生方面有更好的免疫应答和效性,而我们研究认为初次性生活后接种HPV疫苗或仍能有效地降低巴氏涂片检查异常结果,”研究合著者Rebecca Perkins博士解释道,她是波士顿大学医学院妇产科助理教授,同时也是波士顿医学中心的一名妇科医生。

研究期间,41%的受试者至少接种过一次HPV疫苗;其中97%接种于初次性生活后。10%的女性在宫颈细胞学检测后发现有异常结果。至少接种1次HPV疫苗的女性其细胞学异常率比未接种疫苗者下降65%。

为确定HPV疫苗的临床效益,研究人员的持续监测是非常有必要的,特别是疫苗接种率低的地方以及在初次性生活后接种疫苗的年轻女性。“我们应当继续研究比较首次性生活前后接种疫苗的有效性以及疫苗接种的剂量,并探讨疫苗在群体免疫中所起到的作用,”Perkins补充说。

您需要登录后才可以回帖 登录 | 立即注册

本版积分规则

© 2013 艾兰博曼 All Rights Reserved.
( 浙ICP备07020270号-8 )
 
快速回复 返回顶部 返回列表